Category Archives: Molecular Biology

Personal Genomics: Gene Sequencing & Analysis in India.

In recent times, the people of India have been heard talking about gene sequencing, gene editing, gene sequencing and many other similar terms. It seems like, they are now getting introduced to the idea and principle behind personal genomics. Continue reading Personal Genomics: Gene Sequencing & Analysis in India.

What are SNPs? Why are Scientists interested in them?

A most common and important source of genetic variability is known to be present uniformly throughout the genome is termed Single Nucleotide Polymorphisms or SNPs. Interest in SNPs lies in the fact that these polymorphisms may be responsible for the differences in disease susceptibility, drug metabolism and response to environmental factors between individuals. Even, if they are not directly responsible for the disease, they serve as genetic markers for a nearby locus that might be responsible. Continue reading What are SNPs? Why are Scientists interested in them?

How a 2 meters long DNA is fitted into a 2 micrometers Nucleus?

An average Human cell (diploid) contains about 6.4 billion base pairs of DNA divided among 46 chromosomes. The length of each base pair is about 0.34 nm. Therefore, if the DNA molecule in a diploid cell were laid out end to end, the total length of DNA would be approximately 2 meters. Continue reading How a 2 meters long DNA is fitted into a 2 micrometers Nucleus?

Why Nature Preferred DNA over RNA?

It is a well-known fact that DNA acts as a genetic material in most of the organisms on this planet earth. However, it is also clear that RNA also acts a genetic material, but only in some viruses (for example, Tobacco Mosaic Viruses, QB Bacteriophage, etc.).
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Who discovered that DNA is the Genetic Material?

The discovery that genetic information is coded along the length of DNA was one of the major achievements of science in the 20th century. This polymeric molecule, DNA, is the chemical basis of heredity and is the fundamental units of genetic information.
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