How a 2 meters long DNA is fitted into a 2 micrometers Nucleus?

An average Human cell (diploid) contains about 6.4 billion base pairs of DNA divided among 46 chromosomes. The length of each base pair is about 0.34 nm. Therefore, if the DNA molecule in a diploid cell were laid out end to end, the total length of DNA would be approximately 2 meters.Since the diameter of a typical cell nucleus is only 10 μm, it is obvious for us to know that how is it possible to fit 2 meters of DNA in such small space without getting tangled up. The answer lies in the remarkable manner in which a DNA molecule is packaged. […]


Who discovered that DNA is the Genetic Material?

The Journey of genetic material from Nuclein to DNA started with the discovery of Nuclein by Meischer and ended with the Hershey-Chase Experiment. There was a time during this journey when the battle for the title of genetic material was fought between Protein and DNA. But, at the end, DNA unequivocally won the battle and was considered as the genetic material of most of the cell. […]