Nucleic Acid

packaging-of-dna-inside-cell-nucleus
Biology

How a 2 meters long DNA is fitted into a 2 micrometers Nucleus?

May 5, 2018 Vinod Thakur 2

An average Human cell (diploid) contains about 6.4 billion base pairs of DNA divided among 46 chromosomes. The length of each base pair is about 0.34 nm. Therefore, if the DNA molecule in a diploid cell were laid out end to end, the total length of DNA would be approximately 2 meters.Since the diameter of a typical cell nucleus is only 10 μm, it is obvious for us to know that how is it possible to fit 2 meters of DNA in such small space without getting tangled up. The answer lies in the remarkable manner in which a DNA molecule is packaged. […]

DNA-versus-RNA
Biology

Why Nature Preferred DNA over RNA?

April 7, 2018 Vinod Thakur 2

We all know that DNA acts as a genetic material in most of the organisms on this planet earth. However, it is also clear that RNA also acts a genetic material, but only in some viruses. During the evolution, nature has considered DNA over RNA as genetic material, because DNA is more stable and more efficient than RNA. […]

dna-as-the-genetic-material
Biology

Who discovered that DNA is the Genetic Material?

March 24, 2018 Vinod Thakur 2

The Journey of genetic material from Nuclein to DNA started with the discovery of Nuclein by Meischer and ended with the Hershey-Chase Experiment. There was a time during this journey when the battle for the title of genetic material was fought between Protein and DNA. But, at the end, DNA unequivocally won the battle and was considered as the genetic material of most of the cell. […]